BIOMEDIN214

BIOMEDIN 214: Representations and Algorithms for Computational Molecular Biology (BIOE 214, CS 274, GENE 214)Topics: This is a graduate level introduction to bioinformatics and computational biology, algorithms for alignment of biological sequences and structures, BLAST, phylogenetic tree construction, hidden Markov models, basic structural computations on proteins, protein structure prediction, molecular dynamics and energy minimization, statistical analysis of 3D structure, knowledge controlled terminologies for molecular function, expression analysis, chemoinformatics, pharmacogenetics, network biology. Lectures are supplemented with assignments and programming projects, which allow students to implement important computational biology algorithms. Firm prerequisite: CS 106B. NOTE: For students in the Department of Biomedical Data Science Program, this core course MUST be taken as a letter grade only.