IMMUNOL275

Tumor Immunology focuses on the mechanisms by which tumors can escape from and subvert the immune system and conversely on the ability of innate and adaptive arms of the immune system to recognize and eliminate tumors. Topics include: tumor antigens, tumor immunosurveillance and immunoediting, tumor microenvironment, tumor iniduced immunosuppression, tumorimmunotherapy (including cancer vaccines, CARs, TILs, checkpoint antibodies, monoclonal antibodies and bispecific antibodies, as well as bone marrow transplantation and radiation therapy). Tracks the historical development of our understanding of modulating tumor immune response and discusses their relative significance in the light of current research findings. Prerequisite: for undergraduates, human biology or biology core.