BIO246

Synthetic proteins and gene circuits are rapidly evolving technologies that are increasingly central to research and medicine. These proteins and gene circuits are core to next-generation medicines as biologics and cell therapies, research tools that give us unprecedented control over biological processes, and serve as powerful industrial tools. Through lecture and discussion of literature, we will explore key concepts including modularity in synthetic biology, methods of protein and circuit design, and practical applications. We will also discuss how directed evolution, high-throughput screening, and machine learning/artificial intelligence might reshape the landscape of synthetic proteins and gene circuits.